Format

Send to

Choose Destination
Hormones (Athens). 2017 Jan;16(1):5-21. doi: 10.14310/horm.2002.1715.

Vitamin D and aspects of female fertility.

Author information

1
Department of Endocrinology and Diabetes Center, "G. Gennimatas", General Hospital of Athens, Athens, Greece.
2
Endocrine Unit, Department of Pathophysiology, National and Kapodistrian University of Athens, "Laiko" University Hospital, Athens, Greece.
3
Endocrine Unit, 2nd Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, "Aretaieion" University Hospital, Athens, Greece.
4
Department of Biological Chemistry, Medical Scholl, National and Kapodistrian University of Athens, 75 Mikras Asias Str., P.C. 11527, Goudi, Athens, Greece. ekassi@med.uoa.gr.

Abstract

The role of vitamin D in female reproduction has been intensively examined over the last few decades. A large body of evidence suggests that vitamin D might have beneficial effects on metabolic/hormonal parameters of PCOS and endometriosis, while it appears to be associated with IVF outcomes. However, due to the heterogeneity among observational and interventional studies, no cause-effect relationship has yet been established. The aim of this review is to analyze recent in vitro animal and human studies which examined the association of vitamin D with disease entities affecting female fertility potential. Recent research data strongly imply that vitamin D is implicated in female reproduction and might represent a beneficial and inexpensive therapeutic approach, in combination with first-line medical treatments, to female infertility.

PMID:
28500824
DOI:
10.14310/horm.2002.1715
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Springer Icon for Hormones
Loading ...
Support Center