Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Trop Med Hyg. 2017 May;96(5):1248-1252. doi: 10.4269/ajtmh.15-0906.

A Large Outbreak of Thiamine Deficiency Among Illegal Gold Miners in French Guiana.

Author information

1
Equipe EA3593, Ecosystèmes Amazoniens et Pathologie Tropicale, Université des Antilles et de la Guyane, Cayenne, French Guiana, France.
2
Pôle des Centres Délocalisés de Prévention et de Soins, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, France.
3
Unité de Maladies Infectieuses et Tropicales, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, France.
4
Direction Inter-armées du Service de Santé en Guyane, Base de Défense de Guyane, Cayenne, French Guiana, France.
5
Laboratoire Hospitalo Universitaire de Parasitologie et Mycologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, France.
6
Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane, Cayenne, French Guiana, France.

Abstract

AbstractFrom September 2013 to July 2014, several gold miners working in the tropical forest consulted the Maripasoula Health Center in French Guiana for edema and findings consistent with right-sided cardiac failure. Of the 42 cases of beriberi that were diagnosed, one patient died. The laboratory and clinical investigation demonstrated vitamin B1 deficiency in most of the patients tested. Furthermore, 30 of 42 patients responded favorably to 500 mg of intravenous or intramuscular thiamine supplementation. In addition, dietary investigation showed insufficient thiamine intake in these patients. We concluded that patients had acquired beriberi because of diet restrictions, hard labor, and infectious diseases, notably malaria. In 2016, cases were still being reported. We recommend screening for compatible symptoms in gold miners, thiamine supplementation, and nutritional intervention.

PMID:
28500804
PMCID:
PMC5417225
[Available on 2018-05-03]
DOI:
10.4269/ajtmh.15-0906
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Ingenta plc
    Loading ...
    Support Center