Send to

Choose Destination
Am J Ind Med. 2017 Jul;60(7):658-663. doi: 10.1002/ajim.22725. Epub 2017 May 12.

Allergic sinusitis and severe asthma caused by occupational exposure to locust bean gum: Case report.

Author information

Respiratory Health Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia.
John Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Pulmonary and Critical Care Medicine, Penn State Hershey College of Medicine, Hershey, Pennsylvania.


We present a case that highlights the difficulties with diagnosis and the dangers of occupational allergic sinusitis and asthma left unrecognized. We describe the case history of a man who experienced work-related symptoms 1 year after beginning work as a cheesemaker at a creamery, and whose respiratory symptoms progressively worsened over 16 years before an occupational cause of his asthma was identified. His initial discrete episodes of sinusitis and acute bronchitis evolved into persistent asthma of increasing severity with exacerbations requiring repeated emergency room treatment. The case described in our report emphasizes the importance of clinician diagnosis of OA, and subsequent removal from exposure, such that asthma severity does not progress to near-fatal or fatal asthma in the sensitized worker. As demonstrated by this case report, identification of an occupational cause of asthma relies on a high degree of suspicion and excellent detective work by the clinician.


asthmagen; carob bean gum; locust bean gum; occupational asthma; severe asthma

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center