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Med Sci (Paris). 2017 Apr;33(4):410-416. doi: 10.1051/medsci/20173304011. Epub 2017 May 12.

[Phage therapy: a realistic weapon against multidrug resistant bacteria].

[Article in French]

Author information

1
Institut Pasteur, groupe interactions bactériophages bactéries chez l'animal, département de microbiologie, 25, rue du Docteur Roux, 75015 Paris, France - Centre hospitalier René Dubos, Service de réanimation médico-chirurgicale, 95500 Pontoise, France.
2
Institut Pasteur, groupe interactions bactériophages bactéries chez l'animal, département de microbiologie, 25, rue du Docteur Roux, 75015 Paris, France.

Abstract

The continuous increase in antibiotic resistance among bacteria in infectious diseases associated with the lack of new antibiotics able to circumvent them are urging physicians, researchers and politicians to look for others options for treatments. Among those, phage therapy (use of natural viruses that infect bacteria, called bacteriophages) is one of the most promising approaches. In this review, we first focus on the problematic raised by multidrug resistant bacteria before addressing the main biological characteristics of bacteriophages, as well as the credibility and the relevance of phage therapy. We then introduce human applications, their potentials and limits.

PMID:
28497737
DOI:
10.1051/medsci/20173304011
[Indexed for MEDLINE]
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