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Head Neck. 2017 Jul;39(7):1306-1312. doi: 10.1002/hed.24744. Epub 2017 May 8.

Improved outcomes with oral tongue squamous cell carcinoma in Finland.

Author information

1
Department of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
2
Department of Otorhinolaryngology - Head and Neck Surgery, University of Turku and Turku University Hospital, Turku, Finland.
3
Department of Otorhinolaryngology - Head and Neck Surgery, Tampere University Hospital, Tampere, Finland.
4
Department of Otorhinolaryngology - Head and Neck Surgery, Kuopio University Hospital, Kuopio, Finland.
5
Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland.
6
Cancer and Translational Medicine Unit, University of Oulu, Medical Research Unit, Oulu University Hospital.
7
Oral and Maxillofacial Diseases, University of Helsinki, and Haartman Institute, Helsinki, Finland.

Abstract

BACKGROUND:

Incidence rates for oral tongue squamous cell carcinoma (SCC) are steadily rising worldwide.

METHODS:

All patients diagnosed with primary oral tongue SCC at the 5 university hospitals in Finland from 2005 to 2009 were studied. The mean follow-up time was 43 months (median, 54 months; range, 0-111 months).

RESULTS:

Three hundred sixty patients with primary oral tongue SCC were identified. Treatment with curative intent was provided for 328 patients (91%). The 5-year disease-specific survival (DSS) rates were as follows: stage I 87%; stage II 73%; stage III 69%; and stage IV 51%. The 5-year recurrence-free survival in general has improved from 47% in our previous published series (1995-1999) to 65% in the current series (p < .001).

CONCLUSION:

The outcome of oral tongue SCC has significantly improved in Finland. However, the relatively high number of disease recurrences in patients with stage I and II disease, when compared with patients with stage III and IV disease, calls for an investigation of new treatment approaches. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1306-1312, 2017.

KEYWORDS:

metastasis; oral cavity; squamous cell carcinoma; survival; tongue

PMID:
28481417
DOI:
10.1002/hed.24744
[Indexed for MEDLINE]

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