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Biosci Biotechnol Biochem. 2017 Aug;81(8):1461-1465. doi: 10.1080/09168451.2017.1320517. Epub 2017 May 5.

Antimicrobial constituents of peel and seeds of camu-camu (Myrciaria dubia).

Author information

1
a Department of Food and Cosmetic Science , Tokyo University of Agriculture , Abashiri , Japan.

Abstract

Various antimicrobial constituents of camu-camu fruit were isolated. Acylphloroglucinol (compound 1) and rhodomyrtone (compound 2) were isolated from the peel of camu-camu (Myrciaria dubia) fruit, while two other acylphloroglucinols (compounds 3 and 4) were obtained from camu-camu seeds. The structures of the isolated compounds were characterized by spectrophotometric methods. Compounds 1 and 4 were confirmed to be new acylphloroglucinols with different substituents at the C7 or C9 position of 2, and were named myrciarone A and B, respectively. Compound 3 was determined to be isomyrtucommulone B. This is the first report of the isolation of 3 from a natural resource. The antimicrobial activities of compounds 1, 3, and 4 were similar to those of 2, and the minimum inhibitory concentrations were either similar to or lower than that of kanamycin. These results suggest that the peel and seeds of camu-camu fruit could be utilized for therapeutic applications.

KEYWORDS:

Camu-camu; Myrciaria dubia; acylphloroglucinol; antimicrobial activity

PMID:
28475419
DOI:
10.1080/09168451.2017.1320517
[Indexed for MEDLINE]

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