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Proc Natl Acad Sci U S A. 2017 May 16;114(20):5213-5218. doi: 10.1073/pnas.1616736114. Epub 2017 May 4.

African genomes illuminate the early history and transition to selfing in Arabidopsis thaliana.

Author information

1
Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.
2
Department of Structural and Computational Biology, University of Vienna, 1010 Vienna, Austria.
3
Vienna Biocenter, 1030 Vienna, Austria.
4
Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
5
Department of Biology, Chiba University, Chiba 263-8522 Japan.
6
Departamento de Ecología Integrativa, Estación Biológica de Doñana, Consejo Superior de Investigaciones Científicas, 41092 Seville, Spain.
7
Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, 28049 Madrid, Spain.
8
Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany; hancock@mpipz.mpg.de.

Abstract

Over the past 20 y, many studies have examined the history of the plant ecological and molecular model, Arabidopsis thaliana, in Europe and North America. Although these studies informed us about the recent history of the species, the early history has remained elusive. In a large-scale genomic analysis of African A. thaliana, we sequenced the genomes of 78 modern and herbarium samples from Africa and analyzed these together with over 1,000 previously sequenced Eurasian samples. In striking contrast to expectations, we find that all African individuals sampled are native to this continent, including those from sub-Saharan Africa. Moreover, we show that Africa harbors the greatest variation and represents the deepest history in the A. thaliana lineage. Our results also reveal evidence that selfing, a major defining characteristic of the species, evolved in a single geographic region, best represented today within Africa. Demographic inference supports a model in which the ancestral A. thaliana population began to split by 120-90 kya, during the last interglacial and Abbassia pluvial, and Eurasian populations subsequently separated from one another at around 40 kya. This bears striking similarities to the patterns observed for diverse species, including humans, implying a key role for climatic events during interglacial and pluvial periods in shaping the histories and current distributions of a wide range of species.

KEYWORDS:

climate; evolution; migration; population history; self-compatibility

Comment in

PMID:
28473417
PMCID:
PMC5441814
DOI:
10.1073/pnas.1616736114
[Indexed for MEDLINE]
Free PMC Article

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