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Pediatr Infect Dis J. 2017 Oct;36(10):1006-1008. doi: 10.1097/INF.0000000000001634.

Correction of Cerebrospinal Fluid Protein in Infants With Traumatic Lumbar Punctures.

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From the *Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts; †Sections of Pediatric Emergency Medicine and Pediatric Infectious Diseases, Baylor College of Medicine, Houston, Texas; ‡Sections of Pediatric Emergency Medicine and Gastroenterology, Alberta Children's Hospital, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; §Department of Pediatric Emergency Medicine, Children's Minnesota, Minneapolis, Minnesota; ¶Departments of Pediatrics and Emergency Medicine, Yale School of Medicine, New Haven, Connecticut; ‖Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; **Division of Pediatric Emergency Medicine, Hospital for Sick Children, Toronto, Ontario, Canada; ††Department of Emergency Medicine and Pediatrics, University of Michigan, Ann Arbor, Michigan; ‡‡Section of Pediatric Emergency Medicine, Children's Hospital Colorado, Aurora, Colorado; §§Division of Pediatric Emergency Medicine, University of Alabama at Birmingham, Birmingham, Alabama; and ¶¶Departments of Pediatrics and Emergency Medicine, Nemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware.


In our multicenter cohort of infants ≤60 days of age, we identified 2646 infants with a traumatic lumbar puncture, of which 31 (1.2%) had bacterial meningitis. For every 1000 cerebrospinal fluid red blood cells/mm, cerebrospinal (cerebrospinal fluid) protein increased 1.1 mg/dL (95% confidence interval: 1.0-1.2 mg/dL).

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