Send to

Choose Destination
Diab Vasc Dis Res. 2017 May;14(3):172-183. doi: 10.1177/1479164116679775. Epub 2017 Feb 1.

Gaps and barriers in the control of blood glucose in people with type 2 diabetes.

Author information

1 Department of Endocrinology, Ochsner Medical Center, New Orleans, LA, USA.
2 Endocrinology Unit, Javeriana University School of Medicine, Bogotá, Colombia.
3 School of Life & Health Sciences, Aston University, Birmingham, UK.
4 Peking University People's Hospital, Beijing, China.
5 Keenan Research Center in the Li Ka Shing Knowledge Institute, St. Michael's Hospital and Division of Endocrinology & Metabolism, University of Toronto, Toronto, ON, Canada.
6 Diabetes, Metabolism and Endocrinology Center, Quakenbrück Hospital, Quakenbrück, Germany.



Glycaemic control is suboptimal in a large proportion of people with type 2 diabetes who are consequently at an increased and avoidable risk of potentially severe complications. We sought to explore attitudes and practices among healthcare professionals that may contribute to suboptimal glycaemic control through a review of recent relevant publications in the scientific literature.


An electronic search of the PubMed database was performed to identify relevant publications from January 2011 to July 2015. The electronic search was complemented by a manual search of abstracts from key diabetes conferences in 2014/2015 available online.


Recently published data indicate that glycaemic control is suboptimal in a substantial proportion (typically 40%-60%) of people with diabetes. This is the case across geographic regions and in both low- and higher-income countries. Therapeutic inertia appears to be an important contributor to poor glycaemic control in up to half of people with type 2 diabetes. In particular, prescribers are often willing to tolerate extended periods of 'mild' hyperglycaemia as well as having low expectations for their patients. There are often delays of 3 years or longer in initiating or intensifying glucose-lowering therapy when needed.


Many people with type 2 diabetes are failed by current management, with approximately half not achieving or maintaining appropriate target blood glucose levels, leaving these patients at increased and avoidable risk of serious complications. Review criteria: The methodology of this review article is detailed in the 'Methods' section.


Diabetes mellitus; clinical inertia; glycaemic control; review; surveys; type 2

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center