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Muscle Nerve. 2017 Dec;56(6):1171-1173. doi: 10.1002/mus.25679. Epub 2017 May 15.

Age may contribute to the increased frequency of axonal Guillain-Barré syndrome.

Author information

1
Department of Neurology, Division of Critical Care Neurology, Mayo Clinic, Rochester, Minnesota, USA.
2
Department of Neurology, Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina.
3
Department of Pediatric Neurology, Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina.
4
Center for Research on Neuroimmunological Diseases, Raúl Carrea Institute for Neurological Research (FLENI), Montañeses 2325, Buenos Aires, 1428, Argentina.

Abstract

INTRODUCTION:

The frequency of axonal Guillain-Barré syndrome (GBS) varies among countries. Previous studies supporting the high frequency of axonal GBS in South America have been carried out with pediatric populations. We seek to determine the frequency of axonal GBS in both children and adults in South America.

METHODS:

This is a retrospective cohort analysis of patients who were diagnosed with GBS between January 2006 and December 2013 in a neurological center in Buenos Aires, Argentina. Adults and children with a diagnosis of GBS were included and classified by applying Ho and colleagues' criteria1 for axonal GBS.

RESULTS:

The study included 105 patients with GBS. Among 58 adults, only 5 individuals were classified as axonal GBS compared with 16 of 47 children. The frequency of axonal GBS was significantly higher in children than in adults (34% vs. 8.6%, P = 0.0001).

DISCUSSION:

As shown in a cohort of South American patients, age may impact the frequency of axonal GBS. Muscle Nerve 56: 1311-1313, 2017.

KEYWORDS:

AMAN; AMSAM; Argentina; Guillain-Barré syndrome; South America; axonal Guillain-Barré

PMID:
28467012
DOI:
10.1002/mus.25679
[Indexed for MEDLINE]

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