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Mol Neurobiol. 2018 Apr;55(4):3112-3130. doi: 10.1007/s12035-017-0516-4. Epub 2017 May 2.

Exercise as a Positive Modulator of Brain Function.

Author information

1
Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, 77204, USA. kalkadhi@uh.edu.

Abstract

Various forms of exercise have been shown to prevent, restore, or ameliorate a variety of brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders, and sleep deprivation, some of which are discussed here. In this review, the effects on brain function of various forms of exercise and exercise mimetics in humans and animal experiments are compared and discussed. Possible mechanisms of the beneficial effects of exercise including the role of neurotrophic factors and others are also discussed.

KEYWORDS:

Animal voluntary and forced exercise; BDNF; Electrophysiology; Human aerobic and anaerobic exercise; Long-term potentiation; Meditation

PMID:
28466271
DOI:
10.1007/s12035-017-0516-4
[Indexed for MEDLINE]

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