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Sci Rep. 2017 May 2;7(1):1333. doi: 10.1038/s41598-017-01419-7.

Neural connectivity in Internet gaming disorder and alcohol use disorder: A resting-state EEG coherence study.

Park SM1,2, Lee JY1,3, Kim YJ1, Lee JY1,4, Jung HY1,2,4, Sohn BK1,4, Kim DJ5, Choi JS6,7.

Author information

1
Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.
2
Department of Clinical Medical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
3
Interdisciplinary Program in Neuroscience, Seoul National University College of Natural Sciences, Seoul, Republic of Korea.
4
Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, Republic of Korea.
5
Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea.
6
Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea. choijs73@gmail.com.
7
Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, Republic of Korea. choijs73@gmail.com.

Abstract

The present study compared neural connectivity and the level of phasic synchronization between neural populations in patients with Internet gaming disorder (IGD), patients with alcohol use disorder (AUD), and healthy controls (HCs) using resting-state electroencephalography (EEG) coherence analyses. For this study, 92 adult males were categorized into three groups: IGD (n = 30), AUD (n = 30), and HC (n = 32). The IGD group exhibited increased intrahemispheric gamma (30-40 Hz) coherence compared to the AUD and HC groups regardless of psychological features (e.g., depression, anxiety, and impulsivity) and right fronto-central gamma coherence positively predicted the scores of the Internet addiction test in all groups. In contrast, the AUD group showed marginal tendency of increased intrahemispheric theta (4-8 Hz) coherence relative to the HC group and this was dependent on the psychological features. The present findings indicate that patients with IGD and AUD exhibit different neurophysiological patterns of brain connectivity and that an increase in the fast phasic synchrony of gamma coherence might be a core neurophysiological feature of IGD.

PMID:
28465521
PMCID:
PMC5430990
DOI:
10.1038/s41598-017-01419-7
[Indexed for MEDLINE]
Free PMC Article

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