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J Neuropsychiatry Clin Neurosci. 2017 Fall;29(4):391-400. doi: 10.1176/appi.neuropsych.16110310. Epub 2017 May 3.

Preliminary Evidence on Cannabis Effectiveness and Tolerability for Adults With Tourette Syndrome.

Author information

1
From the Department of Psychiatry, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada (EA-J); the Department of Psychiatry, University Health Network, University of Toronto, Toronto, Ontario, Canada (EA-J, PS); Global Medicines Development, AstraZeneca Canada, Inc., Mississauga, Ontario, Canada (LC); the Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada (PC); the Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada (TB); and Youthdale Treatment Centers, Toronto, Ontario, Canada (PS).

Abstract

The authors retrospectively evaluated effectiveness and tolerability of cannabis in 19 adults with Tourette syndrome. Tics scores decreased by 60%, and 18 of the 19 participants were at least "much improved." Cannabis was generally well tolerated, although most participants reported side effects.

KEYWORDS:

Basal Ganglia Disorders; Drug/Psychotherapy Treatment of Neuropsychiatric Disorders; Neuropharmacology; Outcome Studies Biological/Pharmacological

[Indexed for MEDLINE]

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