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Nucleic Acids Res. 1988 Oct 11;16(19):9323-35.

Codon usage in Pseudomonas aeruginosa.

Author information

1
Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, NY 14642.

Abstract

We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.

PMID:
2845370
PMCID:
PMC338709
DOI:
10.1093/nar/16.19.9323
[Indexed for MEDLINE]
Free PMC Article

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