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Complement Ther Clin Pract. 2017 May;27:57-60. doi: 10.1016/j.ctcp.2017.04.003. Epub 2017 Apr 6.

In-vitro susceptibility of methicillin-resistant Stayphylococcus aureus to honey.

Author information

1
Department of Microbiology, Faculty of Medicine, King Abdul Aziz University, Rabigh Branch, 21589, Saudi Arabia. Electronic address: mbhussain1@kau.edu.sa.
2
Department of Microbiology, University of Health Sciences, Khayaban-e-Jamia Punjab, Lahore 54000, Pakistan. Electronic address: zilufa1936@hotmail.com.
3
Department of Pathology, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia. Electronic address: mashwani82@gmail.com.
4
Department of Community Medicine, Faculty of Medicine, King Abdul Aziz University, Rabigh Branch, 21589, Saudi Arabia. Electronic address: nadeemshafique@gmail.com.

Abstract

Wound infections caused by methicillin-resistant Staphylococcus aureus (MRSA) is becoming much complicated and costly to treat as antimicrobial resistance is quite common. Twenty five MRSA strains isolated from infected wounds and three ATCC reference strains were evaluated for their susceptibility to locally produced black seed (Nigella sativa), beri (ZiziphusJujuba) and shain honey (Plectranthus rugosus wall) by agar incorporation assay. Medically graded manuka honey (UMF 21+) was included as control. Locally produced black seed honey inhibited all clinical isolates at mean MIC of 5.5% (v/v), whereas manuka honey at mean MIC of 4.4% (v/v). The other two locally produced honey; beri and shain honey inhibited these isolates at 6.4% and 10.4% (v/v) respectively. The result of the study has demonstrated that indigenous black seed honey has comparable antibacterial activity to manuka honey and thus offers a good new addition to the existing honey resource for the treatment of wound infections.

KEYWORDS:

Antibacterial activity; Black seed honey; Honey; Methicillin-resistant Staphylococcus aureus; Wound infection

PMID:
28438282
DOI:
10.1016/j.ctcp.2017.04.003
[Indexed for MEDLINE]

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