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Curr Cardiol Rep. 2017 Jun;19(6):47. doi: 10.1007/s11886-017-0856-8.

Does Supplementation with Omega-3 PUFAs Add to the Prevention of Cardiovascular Disease?

Author information

1
Department of Internal Medicine, University Hospital of Ioannina, Leoforos St Niarchou, 45500, Ioannina, Greece.
2
University of Cyprus Medical School, Palaios dromos Lefkosias Lemesou No.215/6, 2029 Aglantzia, Nicosia, Cyprus.
3
University of Ioannina Medical School, Leoforos St Niarchou, 45110, Ioannina, Greece. egepi@cc.uoi.gr.

Abstract

PURPOSE OF REVIEW:

Omega-3 fatty acids are increasingly used for the protection of cardiovascular disease. The main but not the sole mechanism of action is the reduction of triglyceride levels. In this review, we summarize the effect of omega-3 supplements on all-cause and cardiovascular mortality, myocardial infarction, and stroke from the relevant randomized controlled trials.

RECENT FINDINGS:

Twenty-one randomized controlled trials assessed omega-3 supplementation on mortality and cardiovascular-related outcomes. From these studies, as well as from the relevant meta-analyses, we found that omega-3 supplements do not exert a consistent benefit for cardiovascular protection. There is uncertainty of a clear profit from omega-3 supplementation in cardiovascular disease.

KEYWORDS:

Cardiovascular; Death; Fish oil; Myocardial infarction; Omega 3; Polyunsaturated fatty acids

PMID:
28432658
DOI:
10.1007/s11886-017-0856-8
[Indexed for MEDLINE]

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