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J Pediatr. 2017 Sep;188:287-290. doi: 10.1016/j.jpeds.2017.03.028. Epub 2017 Apr 18.

Re-Evaluation of Serum Ferritin Cut-Off Values for the Diagnosis of Iron Deficiency in Children Aged 12-36 Months.

Author information

1
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada.
2
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Pediatrics Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Canada.
3
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Pediatrics Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Canada; Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Canada; Department of Pediatrics, St. Michael's Hospital, University of Toronto, Canada.
4
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Canada; Division of Developmental Pediatrics, Holland Bloorview Kids Rehabilitation Hospital, Bloorview Research Institute, Toronto, Canada.
5
Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Department of Nutritional Sciences, University of Toronto, Toronto, Canada; Division of Endocrinology, Department of Medicine, University of Toronto, Toronto, Canada.
6
Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Canada.
7
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Pediatrics Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Canada. Electronic address: patricia.parkin@sickkids.ca.

Abstract

An ongoing challenge has been determining clinically relevant serum ferritin cut-offs in the diagnosis of iron deficiency in children aged 1-3 years. We identified 2 potential clinically relevant serum ferritin cut-off values through their association with clinically important cut-off of hemoglobin as the indicator of anemia.

KEYWORDS:

clinically relevant cut-off values; hemoglobin; iron deficiency; preschool children; restricted cubic spline regression; serum ferritin

PMID:
28431746
DOI:
10.1016/j.jpeds.2017.03.028
[Indexed for MEDLINE]

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