Format

Send to

Choose Destination
Chem Commun (Camb). 2017 May 2;53(36):5020-5023. doi: 10.1039/c7cc02227a.

Identification of Annexin A2 as a target protein for plant alkaloid matrine.

Author information

1
School of Pharmacy, Second Military Medical University, Shanghai, China. yfchai@smmu.edu.cn.

Abstract

Matrine is a plant alkaloid and a major active component in the Chinese medical herb Sophora flavescens. Matrine has shown potent anti-cancer activities but its molecular target(s) and mechanism are still unknown. Using the photo-affinity labeling approach, for the first time, Annexin A2 was identified as a direct-binding target of matrine in cancer cells.

PMID:
28428997
DOI:
10.1039/c7cc02227a
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Royal Society of Chemistry
Loading ...
Support Center