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Clin Transl Sci. 2017 Sep;10(5):337-350. doi: 10.1111/cts.12464. Epub 2017 Apr 18.

Intra-Target Microdosing (ITM): A Novel Drug Development Approach Aimed at Enabling Safer and Earlier Translation of Biological Insights Into Human Testing.

Author information

1
Burt Consultancy, LLC, Durham, North Carolina, USA.
2
Medical Director, Duke Clinical Research Unit, Durham, North Carolina, USA.
3
Department of Anesthesiology, Duke University, Durham, North Carolina, USA.
4
Robert R. and Katherine B. Penn Professor of Mathematics Arts and Sciences Council Chair Professor of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
5
School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK.
6
Reader in Pharmaceutical Science, Lincoln School of Pharmacy, University of Lincoln, Lincoln, Lincolnshire, UK.
PMID:
28419765
PMCID:
PMC5593170
DOI:
10.1111/cts.12464
[Indexed for MEDLINE]
Free PMC Article

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