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Oncotarget. 2017 Apr 25;8(17):28880-28887. doi: 10.18632/oncotarget.16285.

Development of a Taiwan cancer-related fatigue cognition questionnaire: reliability and validity.

Lai SC1, Lin WC2, Chen CH3, Wu SY4,5,6,7.

Author information

1
Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
2
Department of Cancer Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
3
Department of Colorectal Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
4
Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan.
5
Department of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
6
Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
7
Department of Biotechnology, Hungkuang University, Taichung, Taiwan.

Abstract

PURPOSE:

We prospectively designed a Taiwan cancer-related fatigue cognition questionnaire, version 1.0 (TCRFCQ-V1.0), for Taiwanese patients with cancer and investigated the reliability and validity of this questionnaire.

RESULTS:

The completion rate of the TCRFCQ-V1.0 was high (97% of the patients completed all items), and the rate of missing data was low (0.2%-1.1% for each item). Moreover, the Cronbach alpha value was 0.889. We eliminated 5 items because their respective Cronbach alpha values were higher than the total mean value of Cronbach's alpha. Overall, the TCRFCQ-V1.0 had adequate Cronbach alpha coefficients (range, from 0.882 to 0.889). In addition, the results of Bartlett's test were significant (chi-squared, 2390.11; p < 0.001), indicating the appropriateness of factor analysis. Sampling adequacy was confirmed by the Kaiser-Meyer-Olkin statistic of 0.868. Through exploratory factor analysis, we identified 6 factors with eigenvalues of > 1, and the scree plot indicated no flattening factors. Overall, 28 items achieved a factor loading of ≥ 0.55.

MATERIALS AND METHODS:

We enrolled patients with cancer who were aged > 18 years, had received a pathological diagnosis of cancer, and had undergone cancer treatments such as surgery, chemotherapy, radiotherapy, or concurrent chemoradiotherapy at a single institute in Taiwan. Of the identified 167 eligible patients, 161 (96.4%) were approached. Of these patients, 6 (7.2%) declined to participate and 155 (92.8%) were interviewed. The initial 43 items in the TCRFCQ-V1.0 were assessed for ceiling and floor effects.

CONCLUSIONS:

The TCRFCQ-V1.0 is a reliable and valid instrument for measuring CRF cognition in Taiwanese patients with cancer.

KEYWORDS:

cancer-related fatigue questionnaire; reliability; validity

PMID:
28418869
PMCID:
PMC5438699
DOI:
10.18632/oncotarget.16285
[Indexed for MEDLINE]
Free PMC Article

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