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J Arrhythm. 2017 Apr;33(2):130-133. doi: 10.1016/j.joa.2016.08.003. Epub 2016 Sep 12.

Comparison of the measured pre-ejection periods and left ventricular ejection times between echocardiography and impedance cardiography for optimizing cardiac resynchronization therapy.

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Department of Cardiology, Iwate Prefectural Central Hospital, Morioka 020-0066, Iwate, Japan.



The pre-ejection period (PEP) and left ventricular ejection time (LVET) are easily measured by impedance cardiography (ICG). We hypothesized that the PEP/LVET measured by ICG would correlate with that measured by echocardiography, and that PEP/LVET measured by ICG would be useful for cardiac resynchronization therapy (CRT) optimization.


Newly CRT implanted patients were optimized by echocardiography. The PEP/LVET was measured by echocardiography and ICG in two different settings: optimized setting and right ventricle (RV)-only pacing.


The PEP/LVET was significantly decreased in the optimized setting compared with that in RV-only pacing (0.62±0.13 vs 0.75±0.16, p<0.05). The PEP/LVET values calculated by ICG and echocardiography were positively correlated (r=0.553, p=0.003).


ICG was useful for the optimization of CRT.


Cardiac resynchronization therapy; Echocardiogram; Impedance cardiography

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