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Lancet Neurol. 2017 May;16(5):399-408. doi: 10.1016/S1474-4422(17)30078-9.

Increasing value and reducing waste in stroke research.

Author information

1
Department of Internal Medicine and Cardiology, Oslo University Hospital, Oslo, Norway. Electronic address: eivind.berge@medisin.uio.no.
2
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
3
Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands.
4
Department of Neuroscience, CRCHUM, University of Montreal, QC, Canada.
5
Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
6
Stroke Service, Mater University Hospital, Dublin, Ireland; Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland.
7
Department of Neurology, Academic Medical Center, Amsterdam, the Netherlands.
8
Medical Sciences Division, University of Oxford, Oxford, UK.

Abstract

Stroke is a major burden to patients and society, and resources spent on stroke research must be used efficiently and produce good value in terms of improvements in human health. However, many instances of poor value from stroke research funding have resulted from the way in which stroke research topics have been chosen and how studies have been designed, conducted, analysed, regulated, managed, disseminated, or reported. A cooperative effort of European stroke researchers aimed to identify sources of inefficiency and waste, recommend approaches to increase value, and highlight examples of best practice in stroke research. Evidence suggests that progress has been made, but there is room for much improvement; researchers, funders, regulators, and other stakeholders in stroke research might consider these recommendations when planning new research.

PMID:
28414653
DOI:
10.1016/S1474-4422(17)30078-9
[Indexed for MEDLINE]

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