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J Infect Chemother. 2017 Sep;23(9):655-657. doi: 10.1016/j.jiac.2017.03.011. Epub 2017 Apr 10.

Analysis of IMP-1 type metallo-β-lactamase-producing Acinetobacter radioresistens isolated from companion animals.

Author information

1
Miyamoto Animal Hospital, 2265-8 Kurokawa, Yamaguchi City, Yamaguchi 753-0851, Japan; Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi City, Yamaguchi 753-8515, Japan.
2
Miyamoto Animal Hospital, 2265-8 Kurokawa, Yamaguchi City, Yamaguchi 753-0851, Japan.
3
Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan.
4
Department of Microbiology and Infectious Diseases, Toho University School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan. Electronic address: yishii@med.toho-u.ac.jp.
5
Faculty of Agriculture, Tottori University, 4-101 Koyamacho Minami, Tottori City, Tottori 680-8550, Japan.
6
Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi City, Yamaguchi 753-8515, Japan.
7
Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku Ourai Kita, Izumisano City, Osaka 598-8531, Japan.

Abstract

IMP-1 type metallo-β-lactamase-producing (MBL-producing) Acinetobacter radioresistens was isolated from a dog with cystitis and a cat with conjunctivitis. The MBL-producing A. radioresistens isolates were resistant to all of the β-lactam antibiotics used in the sensitivity tests, but were susceptible to gentamicin, amikacin, and minocycline. Also, one of the two strains of A. radioresistens was susceptible to ciprofloxacin and levofloxacin. These two cases were cured by administration of tetracyclines and fluoroquinolones, which elicited a positive result in the sensitivity tests. This report of the isolation of MBL-producing A. radioresistens in companion animals is the first in the world. To prevent the proliferation of MBL-producing bacteria, veterinary hospitals need to be aware of the behavior of MBL-producing organisms.

KEYWORDS:

Acinetobacter radioresistens; Antibiotic resistance; Antibiotic susceptibility; Companion animal; Metallo-β-lactamase; bla(IMP-1)

PMID:
28408304
DOI:
10.1016/j.jiac.2017.03.011
[Indexed for MEDLINE]

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