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PLoS One. 2017 Apr 12;12(4):e0173054. doi: 10.1371/journal.pone.0173054. eCollection 2017.

Fruit consumption and physical activity in relation to all-cause and cardiovascular mortality among 70,000 Chinese adults with pre-existing vascular disease.

Author information

1
School of Public Health, Shandong University, Jinan, Shandong, China.
2
Qingdao Center for Disease Prevention and Control, Qingdao, Shandong, China.
3
Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
4
Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
5
Dept. of Epidemiology, School of Public Health, Peking University Health Science Center, Beijing, China.
6
Chinese Academy of Medical Sciences, Beijing, China.
7
China National Center for Food Safety Risk Assessment, Beijing, China.
8
Suzhou CDC, Suzhou, Jiangsu Province, China.
9
Meilan CDC, Haikou, Hainan Province, China.

Abstract

OBJECTIVES:

To assess the associations of fresh fruit consumption and total physical activity with all-cause and cardiovascular mortality among Chinese adults who have been diagnosed with cardiovascular disease (CVD) or hypertension.

METHODS:

During 2004-08, the China Kadoorie Biobank study recruited 70,047 adults, aged 30-79 years, with physician-diagnosed stroke or transient ischaemic attack, ischemic heart disease, or hypertension. Information on diet and physical activity was collected using an interviewer-administered electronic questionnaire. Cox regression was used to yield hazard ratios (HRs) for the independent and joint associations of fresh fruit consumption and total physical activity with mortality.

RESULTS:

At baseline, 32.9% of participants consumed fresh fruit regularly (i.e. >3 days/week) and the mean total physical activity were 15.8 (SD = 11.8) MET-hr/day. During ~7-years follow-up, 6569 deaths occurred with 3563 from CVD. Compared to participants with <1 day/week fruit consumption, regular consumers had HR (95% CI) of 0.84 (0.79-0.89) for all-cause mortality and 0.79 (0.73-0.86) for CVD mortality. The HRs for the top vs bottom tertile of physical activity were 0.68 (0.64-0.72) and 0.65 (0.60-0.71), respectively, with no clear evidence of reverse causality. After correcting for regression dilution, each 100 g/day usual consumption of fresh fruit or 10 MET-hr/day usual levels of physical activity was associated with 23-29% lower mortality. The combination of regular fruit consumption with top 3rd of physical activity (>16.53 MET-hr/day) was associated with about 40% lower mortality.

CONCLUSION:

Among Chinese adults with pre-existing vascular disease, higher physical activity and fruit consumption were both independently and jointly associated with lower mortality.

PMID:
28403155
PMCID:
PMC5389797
DOI:
10.1371/journal.pone.0173054
[Indexed for MEDLINE]
Free PMC Article

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