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Nature. 1988 Jul 28;334(6180):314-9.

Transcriptional autoregulation of the proto-oncogene fos.

Author information

1
Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92138.

Abstract

Serum-induced transcription of the proto-oncogene fos is under negative feedback regulation mediated by the fos protein. The fos promoter region responsive to repression is also required for serum inducibility and binds a nucleoprotein complex in which the nuclear factor AP-1 is associated with fos protein.

PMID:
2839774
DOI:
10.1038/334314a0
[Indexed for MEDLINE]

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