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Mediators Inflamm. 2017;2017:6869259. doi: 10.1155/2017/6869259. Epub 2017 Mar 14.

Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease.

Author information

1
College of Animal Science and Technology, Hunan Agriculture University, Changsha, Hunan 410128, China; Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Hunan 410125, China; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan 410125, China; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan 410125, China.
2
Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Hunan 410125, China; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan 410125, China; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Animal Production Safety, CICAPS, Changsha 410128, China.
3
Guangdong Wangda Group Academician Workstation for Clean Feed Technology Research and Development in Swine, Guangdong Wangda Group Co., Ltd., Guangzhou, Guangdong 510663, China.
4
College of Animal Science and Technology, Hunan Agriculture University, Changsha, Hunan 410128, China; Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Hunan 410125, China; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan 410125, China; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Animal Production Safety, CICAPS, Changsha 410128, China.

Abstract

Inflammatory Bowel Disease (IBD) is a kind of chronic inflammation, which has increasing incidence and prevalence in recent years. IBD mainly divides into Crohn's disease (CD) and ulcerative colitis (UC). It is hard to cure IBD completely, and novel therapies are urgently needed. Amino acids (AAs) and their metabolites are regarded as important nutrients for humans and animals and also play an important role in IBD amelioration. In the present study, the potential protective effects of AAs and their metabolites on IBD had been summarized with the objective to provide insights into IBD moderating using dietary AAs and their metabolites as a potential adjuvant therapy.

PMID:
28392631
PMCID:
PMC5368367
DOI:
10.1155/2017/6869259
[Indexed for MEDLINE]
Free PMC Article

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