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Eur J Surg Oncol. 2017 Aug;43(8):1402-1408. doi: 10.1016/j.ejso.2017.03.014. Epub 2017 Mar 27.

Immediate lipofilling in breast conserving surgery.

Author information

1
Edinburgh Breast Unit, NHS Lothian, Western General Hospital, Edinburgh, UK. Electronic address: lucykhan@doctors.org.uk.
2
Edinburgh Breast Unit, NHS Lothian, Western General Hospital, Edinburgh, UK. Electronic address: cameron.raine@nhslothian.scot.nhs.uk.
3
Edinburgh Breast Unit, NHS Lothian, Western General Hospital, Edinburgh, UK. Electronic address: mike.dixon@ed.ac.uk.

Abstract

BACKGROUND:

The aim of breast conserving surgery (BCS) is to excise the cancer with clear margins whilst at the same time leaving a good or excellent cosmetic result. A significant percentage of women, who have large cancers or have limited breast volumes, achieve poor cosmetic outcomes. BCS with immediate volume replacement using lipofilling or autologous fat transfer is a new technique. The aim of this study was to evaluate the cosmetic outcomes of a pilot study of patients having BCS and immediate lipofilling performed in The Edinburgh Breast Unit.

METHODS:

Questionnaires were mailed to 35 women who had BCS with immediate lipofilling and completed by 32 and results compared with those from a contemporary series of 39 women who had BCS alone. The cancers were significantly larger in the lipofilling group (median 21 mm vs. 16 mm p = 0.011) and the patients were non-significantly younger (median age 49 years vs. 54 p = 0.06).

RESULTS:

At a median follow-up of 36 months, results from the Breast Q™ questionnaire showed significantly better cosmetic outcomes with lipofilling (most p < 0.001) and less local breast symptoms (p = 0.0045). There have been no local recurrences in either group and only 1 of the 35 patients was recalled following post-operative surveillance annual mammography.

CONCLUSION:

BCS and immediate lipofilling provides superior cosmetic outcomes to standard BCS.

KEYWORDS:

Autologous fat transfer; Breast cancer; Breast conserving surgery; Cosmetic outcome; Lipofilling

PMID:
28390738
DOI:
10.1016/j.ejso.2017.03.014
[Indexed for MEDLINE]

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