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J Diet Suppl. 2017 Apr 7:1-14. doi: 10.1080/19390211.2017.1304484. [Epub ahead of print]

A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness and Safety of a Thermogenic Supplement in Addition to an Energy-Restricted Diet in Apparently Healthy Females.

Author information

1
a Bodybuilding.com , Boise , ID , USA.
2
b Department of Human Sciences , College of Education and Human Ecology, The Ohio State University , Columbus , OH , USA.
3
c Clinical Trials Unit, University of Kansas Medical Center - Wichita Campus , Wichita , KS , USA.
4
d Molecular and Applied Sciences Laboratory , School of Kinesiology, Auburn University , Auburn , AL , USA.
5
e Health and Wellness, Mercy Hospital , Springfield , MO , USA.
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f Metropolitan State University , Denver , CO , USA.
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g School of Health Sciences , American Public University System , Charles Town , WV , USA.
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h Department of Cell Biology and Physiology , Edward Via College of Osteopathic Medicine - Auburn Campus , Auburn , AL , USA.

Abstract

The increasing interest in weight loss has seen a concurrent rise in the supplemental use of thermogenics to aid weight loss efforts. To date, the effectiveness and safety of supplemental proprietary blend thermogenics, in conjunction with high-protein energy-restricted diets have not been thoroughly evaluated. The purpose of this study was to investigate the efficacy of a low-calorie, high-protein diet with and without the concomitant use of a thermogenic supplement on body weight and body composition in apparently healthy females. Subjects were divided into three groups, Bizzy Diet+FitMiss Burn (BURN, N = 12), Bizzy Diet+Placebo (PLA, N = 13), and Control (CON, N = 14), and underwent two testing sessions separated by approximately 3 weeks. Resting blood pressure (BP), resting heart rate (RHR), clinical safety markers, body weight (BW), and body composition were assessed during each testing session. Repeated measures analysis of variance (ANOVA) revealed a significant effect for time relative to BW, total body fat mass (FM), leg FM, and trunk FM. Post hoc analysis revealed that the BURN and PLA groups experienced significant decreases in both BW and total body FM compared to CON (p <.05). There were no significant interactions for BP, RHR, or clinical safety markers over the course of the study. The Bizzy Diet, both with and without the addition of FitMiss Burn thermogenic, appears to be safe for short-term use and may lead to greater improvement in body composition and BW in an apparently healthy female population.

KEYWORDS:

body composition; body fat; nutrition; supplementation; weight loss

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