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Asia Pac J Ophthalmol (Phila). 2017 May-Jun;6(3):228-232. doi: 10.22608/APO.2016197. Epub 2017 Mar 29.

Corneal Collagen Crosslinking for Post-LASIK Ectasia: An Australian Study.

Author information

1
Sydney Cornea Clinic, Sydney, Australia.
2
Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
3
Vision Eye Institute, Chatswood, Australia.
4
Save Sight Institute, Sydney Medical School, University of Sydney, Sydney, Australia.
5
South West Vision Institute, Liverpool, New South Wales, Australia.

Abstract

PURPOSE:

Post laser-assisted in situ keratomileusis (LASIK) ectasia is a rare and unpredictable complication after LASIK. Corneal collagen crosslinking (CXL) has emerged as a promising technique to address this complication. Our study evaluates the long-term efficacy of CXL for post-LASIK ectasia in an Australian setting.

DESIGN:

Retrospective review of post-LASIK ectasia patients referred to and treated at 3 corneal refractive surgery institutions in Sydney, Australia.

METHODS:

Eleven patients (14 eyes; mean age, 39.7 ± 12.6 years) underwent epithelium-off CXL with follow-up ranging from 12-78 months. Best spectacle-corrected visual acuity (BSCVA), simulated keratometry, corneal topography indices, and higher-order aberrations (HOAs) [mean ± standard error of the mean (SEM)] were measured with a rotating Scheimpflug camera (Pentacam, Oculus). Comparisons between baseline measurements and postoperative outcomes were performed using paired t test analysis.

RESULTS:

At last follow-up, BSCVA improved significantly by 0.2 ± 0.06 logMAR (P = 0.01), and 12 of 14 eyes showed no keratometric deterioration. Of the corneal topography indices, index of height asymmetry showed a trend toward a significant improvement (P = 0.05). There was no progression of corneal HOAs. Central corneal thickness was not significantly altered (P = 0.6). No major postoperative complications were observed.

CONCLUSIONS:

In the Australian setting, CXL has proven effective at stabilizing the progression of post-LASIK ectasia, inducing corneal regularity, and improving visual acuity.

KEYWORDS:

refractive surgery; LASIK; crosslinking; ectasia

PMID:
28379654
DOI:
10.22608/APO.2016197
[Indexed for MEDLINE]
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