Format

Send to

Choose Destination
Br J Surg. 2017 Aug;104(9):1244-1249. doi: 10.1002/bjs.10527. Epub 2017 Apr 4.

Evaluation of the peritoneal carcinomatosis index with CT and MRI.

Author information

1
Department of Body and Interventional Imaging, Hôpital Lariboisière, Assistance Publique - Hôpitaux de Paris (AP-HP), Université Diderot-Paris 7 and Institut National de la Santé et de la Recherche Médicale (INSERM) U965, AP-HP, Paris, France.
2
Department of Radiology, McGill University Health Centre, Montreal, Quebec, Canada.
3
Department of Radiology, Hôpital Robert-Debré, Reims, France.
4
INSERM-Unité Mixte de Recherche en Santé 1138 Team 22, Cordeliers Research Centre, Paris Descartes University, Department of Medical Informatics and Public Health, European George Pompidou Hospital, AP-HP, Paris, France.
5
Department of Radiology, Centre Hospitalier Lyon Sud - Hospices Civils de Lyon, Lyon 1 University, Equipe Mixte de Recherche 3738, Lyon, France.
6
Department of Digestive and Oncological Surgery, Centre Hospitalier Lyon Sud - Hospices Civils de Lyon, Lyon 1 University, Equipe Mixte de Recherche 3738, Lyon, France.

Abstract

BACKGROUND:

The aim was to determine the incremental value of MRI compared with CT in the preoperative estimation of the peritoneal carcinomatosis index (PCI).

METHODS:

CT and MRI examinations of patients with peritoneal carcinomatosis were evaluated. CT images were first analysed by two observers who determined a first PCI (PCICT ). Then, the two observers reviewed MRI examinations in combination with CT and determined a second PCI (PCICT+MRI ). The sensitivity and negative predictive value of the two imaging sets were determined using surgery as a reference standard (PCIRef ).

RESULTS:

CT plus MRI was more accurate in predicting the surgical PCI than CT alone. The absolute difference between PCICT+MRI and PCIRef was lower than that between PCICT and PCIRef (mean(s.d.) 3·96(4·10) versus 4·89(4·73); P = 0·010). The number of true-positive findings increased from 106 to 125 for reader 1 and from 117 to 132 for reader 2 with the adjunct of MRI. For both readers, an increased sensitivity was obtained when both MRI and CT were used (from 63 to 81 per cent for reader 1; from 44 to 81 per cent for reader 2). The increase in sensitivity was greater for patients with a moderate volume of disease.

CONCLUSION:

The combination of CT and MRI improved the preoperative estimation of PCI compared with CT alone.

PMID:
28376270
DOI:
10.1002/bjs.10527
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center