Format

Send to

Choose Destination
J Pathol Transl Med. 2017 May;51(3):320-324. doi: 10.4132/jptm.2016.09.07. Epub 2017 Apr 4.

Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report.

Author information

1
Department of Pathology, Eulji University School of Medicine, Daejeon, Korea.
2
Department of Radiology, Eulji University School of Medicine, Daejeon, Korea.
3
Department of Surgery, Eulji University School of Medicine, Daejeon, Korea.

Abstract

Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.

KEYWORDS:

Eosinophils; Ganglionitis; Pseudo-obstruction

Supplemental Content

Full text links

Icon for Publishing M2Community Icon for PubMed Central
Loading ...
Support Center