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Clin Liver Dis. 2017 May;21(2):289-301. doi: 10.1016/j.cld.2016.12.004. Epub 2017 Feb 23.

Extended Criteria Donors in Liver Transplantation.

Author information

1
Division of Gastroenterology and Hepatology, University of California, San Diego, 200 West Arbor Drive M/C 8413, San Diego, CA, USA. Electronic address: ivodkin@ucsd.edu.
2
Division of Gastroenterology and Hepatology, University of California, San Diego, 200 West Arbor Drive M/C 8413, San Diego, CA, USA.

Abstract

Mortality rates on the liver transplant waiting list are increasing. The shortage of organs has resulted in higher utilization of extended criteria donors (ECDs), with centers pushing the limits of what is acceptable for transplantation. Donor quality is more appropriately represented as a continuum of risk, and careful selection and matching of ECD grafts with recipients may lead to excellent outcomes. Although there is no precise definition for what constitutes an ECD liver, this review focuses on frequently cited characteristics, including donor age, steatosis, donation after cardiac death, and donors with increased risk of disease transmission.

KEYWORDS:

Centers for Disease Control and Prevention high-risk donors; Disease transmission; Donation after cardiac death; Extended criteria donor; Liver transplantation

PMID:
28364814
DOI:
10.1016/j.cld.2016.12.004
[Indexed for MEDLINE]

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