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Noro Psikiyatr Ars. 2014 Mar;51(1):30-39. doi: 10.4274/npa.y6565. Epub 2014 Mar 1.

The Effect of Sertraline on the Quality of Life for Children and Adolescents with Anxiety Disorder.

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Kocaeli University Faculty of Medicine, Child and Adolescent Mental Health and Department of Medicine, Kocaeli, Turkey.
Kocaeli University Faculty of Medicine, Department of Public Health, Kocaeli, Turkey.


in English, Turkish


In this study, we aimed to determine the changes in quality of life of children/adolescents with anxiety disorders during six months of sertraline treatment, to investigate parent-child/adolescent concordance in perception of quality of life and to examine the effect of treatment on children/adolescents.


In this study, 30 patients with anxiety disorders according to criteria specified in Diagnostic and Statistical Manual of Mental Disorders, 4th. Edition (DSM-IV) were assigned to sertraline treatment. The patients were evaluated using the Pediatric Quality of Life Inventory (PedsQL), State-Trait Anxiety Inventory for Children, Clinical Global Impression Scale (CGI) and the Children's Global Assessment Scale (CGAS) at 0th, 2nd and 6th months.


PedsQL total scores increased significantly with the treatment in children and adolescents (p<.001), however, no differences were observed in parent proxy report (p=.326). The mean CGAS score was 59.85±7.73 at the beginning of treatment and 73.70±7.01 at the end of treatment (p<.001). The average CGI score decreased from 4.68±.96 to 2.27±.84.


It was observed that perception of quality of life in children and adolescents with anxiety disorders increased with the treatment.


Anxiety disorders; adolescents; child; quality of life

Conflict of interest statement

Conflict of interest: The authors reported no conflict of interest related to this article. Çıkar çatışması: Yazarlar bu makale ile ilgili olarak herhangi bir çıkar çatışması bildirmemişlerdir.

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