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J Clin Orthop Trauma. 2017 Jan-Mar;8(1):85-88. doi: 10.1016/j.jcot.2016.09.008. Epub 2016 Sep 30.

Intra-articular hyaluronic acid is superior to steroids in knee osteoarthritis: A comparative, randomized study.

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1
Department of Orthopaedics and Joint Replacement Surgery, Indraprastha Apollo Hospitals, New Delhi 110076, India.

Abstract

BACKGROUND:

To compare the short and mid-term results of intraarticular triamcinolone hexacetonide and hyaluronic acid (HA) in knee osteoarthritis.

METHODS:

A prospective randomized study including 40 patients in steroid and 42 patients in HA group. The outcome was evaluated with Knee Society Score (KSS) and Visual Analog Scale (VAS).

RESULT:

On KSS function and VAS score, there was no difference till four weeks. On KSS pain there was no difference till 12 weeks (P > 0.05) after that score of steroid group deteriorated rapidly. At six months HA was significantly better than a steroid.

CONCLUSION:

The HA seems to be better for pain relief and functionality in the short and mid-term periods.

KEYWORDS:

Hyaluronic acid; Intra-articular; Knee Society Score; Osteoarthritis; Steroid

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