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COPD. 2017 Aug;14(4):401-410. doi: 10.1080/15412555.2017.1298583. Epub 2017 Mar 24.

Practical Insight to Monitor Home NIV in COPD Patients.

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a Réanimation Polyvalente , Hôpital Sainte Musse , Toulon Cedex , France.
b VitalAire France , Air Liquide HealthCare , Gentilly , France.
c AP-HP, Respiratory Physiology Department , Cochin Hospital, René Descartes University , Paris , France.


Home noninvasive ventilation (NIV) is used in COPD patients with concomitant chronic hypercapnic respiratory failure in order to correct nocturnal hypoventilation and improve sleep quality, quality of life, and survival. Monitoring of home NIV is needed to assess the effectiveness of ventilation and adherence to therapy, resolve potential adverse effects, reinforce patient knowledge, provide maintenance of the equipment, and readjust the ventilator settings according to the changing condition of the patient. Clinical monitoring is very informative. Anamnesis focuses on the improvement of nocturnal hypoventilation symptoms, sleep quality, and side effects of NIV. Side effects are major cause of intolerance. Screening side effects leads to modification of interface, gas humidification, or ventilator settings. Home care providers maintain ventilator and interface and educate patients for correct use. However, patient's education should be supervised by specialized clinicians. Blood gas measurement shows a significant decrease in PaCO2 when NIV is efficient. Analysis of ventilator data is very useful to assess daily use, unintentional leaks, upper airway obstruction, and patient ventilator synchrony. Nocturnal oximetry and capnography are additional monitoring tools to assess the impact of NIV on gas exchanges. In the near future, telemonitoring will reinforce and change the organization of home NIV for COPD patients.


Chronic obstructive pulmonary disease; hypoventilation, noninvasive ventilation; respiratory therapy

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