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Mol Biol Evol. 1988 Jan;5(1):21-9.

The structure and evolution of the spider monkey delta-globin gene.

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Department of Medical Genetics and Pediatrics, University of Wisconsin--Madison 53706.


We have isolated the delta-globin gene of the New-World spider monkey, Ateles geoffroyi, and compared its nucleotide sequence with those of other primate delta- and beta-globin genes. Among primate delta-globin genes, the rate of nonsynonymous substitutions is much less than the rate of synonymous substitutions. This suggests that primate delta-globin genes may remain under evolutionary conservation, perhaps because hemoglobin A2 has an as yet unknown physiological importance.

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