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Diagn Microbiol Infect Dis. 2017 Jan;87(1):25-27. doi: 10.1016/j.diagmicrobio.2016.08.022. Epub 2016 Aug 28.

Comparison of Cobas® HPV and Anyplex™ II HPV28 assays for detecting and genotyping human papillomavirus.

Author information

1
INSERM U1043, CPTP, CHU Purpan, BP 3028, F-31024 Toulouse, France; Université de Toulouse, UPS, CPTP, F-31024 Toulouse, France; Laboratoire de Virologie, CHU de Toulouse, Hôpital Purpan, F-31059 Toulouse, France. Electronic address: pasquier.c@chu-toulouse.fr.
2
INSERM U1043, CPTP, CHU Purpan, BP 3028, F-31024 Toulouse, France; Université de Toulouse, UPS, CPTP, F-31024 Toulouse, France; Laboratoire de Virologie, CHU de Toulouse, Hôpital Purpan, F-31059 Toulouse, France.
3
Laboratoire de Virologie, CHU de Toulouse, Hôpital Purpan, F-31059 Toulouse, France.
4
Université de Toulouse, UPS, CPTP, F-31024 Toulouse, France; Laboratoire de Virologie, CHU de Toulouse, Hôpital Purpan, F-31059 Toulouse, France; Pathology and Cytology Department, CHU de Toulouse, IUCT, F-31059 Toulouse, France.

Abstract

Persistent infection with high-risk human papillomavirus (HPV-HR) is a recognized cause of cervical cancer. The aim of this study was to compare analytical and clinical performances of the Cobas® HPV and Anyplex™ II HPV28 assays for HPV detection and genotyping. A total of 94 cervical samples were tested. For HPV-HR, the results agreed very well (94.68%), with 100% agreement when detecting CIN2+. The Anyplex™ II HPV28 assay detected more genotypes than the Cobas® HPV Test, but their clinical performances were similar.

KEYWORDS:

Anyplex™ II HPV28; HPV genotyping; Human papillomavirus; Real-time PCR

[Indexed for MEDLINE]

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