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Dermatol Online J. 2016 Dec 15;22(12). pii: 13030/qt15f65047.

Gardner-Diamond syndrome.

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Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.


Gardner-Diamond syndrome, which also is knownas autoerythrocyte sensitization disorder, is a raresyndrome of inflammatory, edematous papulesthat evolve into painful ecchymoses on the trunkand lower legs after a period of stress with no priorhistory of trauma. This syndrome usually occurs inwomen with a history of psychiatric disorders, themost common one being depression. Although theexact mechanism of injury is not well understood,it is hypothesized that these patients haveautoantibodies to phosphatidylserine, which is aphospholipid membrane component in erythrocytes.Treatment for this disorder includes symptomatictherapies and psychotropic medications to treat theunderlying psychiatric disorder.

[Indexed for MEDLINE]

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