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Interact Cardiovasc Thorac Surg. 2017 Jun 1;24(6):882-889. doi: 10.1093/icvts/ivx016.

Mid-term results of zone 0 thoracic endovascular aneurysm repair after ascending aorta wrapping and supra-aortic debranching in high-risk patients.

Author information

1
Cardiovascular Surgery Unit, University Hospital Zurich, Zurich, Switzerland.
2
University of Palermo, Vascular Surgery Unit, AOUP "P. Giaccone", Palermo, Italy.
3
New York University Medical Center, New York, NY, USA.
4
Interventional Radiology, University Hospital Zurich, Zurich, Switzerland.
5
Department of Vascular Surgery, San Filippo Neri Hospital, Rome, Italy.
6
Institute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland.
7
Department of Anesthesiology and Intensive Care Medicine, Cantonal Hospital of Muensterlingen, Muensterlingen, Switzerland.

Abstract

OBJECTIVES:

Surgical repair of aneurysmal disease involving the ascending aorta, aortic arch and eventually the descending aorta is generally associated with significant morbidity and mortality. A less invasive approach with the ascending wrapping technique (WT), supra-aortic vessel debranching (SADB) and thoracic endovascular aneurysm repair (TEVAR) in zone 0 was developed to reduce the associated risk in these patients.

METHODS:

During a 10-year period, consecutive patients treated by the ascending WT, SADB and TEVAR in zone 0 were included. All patients were considered at high risk for conventional surgery. Measured outcomes included perioperative deaths and morbidity, maximal aortic transverse diameter (TD) and its postoperative evolution, endoleak, survival, freedom from cardiovascular reinterventions, SADB freedom from occlusion and aortic valve function during follow-up. Median follow-up was 37.4 [mean = 34; range, 0-65; standard deviation (SD) = 20] months.

RESULTS:

Twenty-six cases were included with a mean age of 71.88 ( r  = 56-87; SD = 8) years. A mean of 2.9 supra-aortic vessels (75) per patient was debranched from the ascending aorta. The mean time interval from WT/SADB and TEVAR was 29 ( r  = 0-204; SD = 48) days. TEVAR was associated with chimney and/or periscope grafts in 6 (23%) patients, and extra-anatomical supra-aortic bypasses were performed in 6 (23%) patients. Perioperative mortality was 7.7% (2/26). Neurological events were registered in 3 (11.5%) cases, and a reintervention was required in 3 (11.5%) cases. After the WT, the ascending diameter remained stable during the follow-up period in all cases. At mean follow-up, significant shrinkage of the arch/descending aorta diameter was observed. A type I/III endoleak occurred in 3 cases. At 5 years, the rates of survival, freedom from cardiovascular reinterventions and SADB freedom from occlusion were 71.7, 82.3 and 96%, respectively.

CONCLUSIONS:

The use of the ascending WT, SADB and TEVAR in selected patients with complex thoracic aorta disease is safe and shows promising mid-term results at 3 years. The combination of these techniques could represent an alternative to the standard open surgical repair, especially in older patients or in patients unfit for cardiopulmonary bypass.

KEYWORDS:

Aneurysm; Arch; Ascending; Debranching; TEVAR; Wrapping

PMID:
28329189
DOI:
10.1093/icvts/ivx016
[Indexed for MEDLINE]

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