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J Oral Biol Craniofac Res. 2017 Jan-Apr;7(1):49-53. doi: 10.1016/j.jobcr.2015.11.007. Epub 2016 Feb 4.

Miracle cells for natural dentistry - A review.

Author information

1
Professor and Head, Department of Paedodontics and Preventive Dentistry, D J College of Dental Sciences and Research, Modinagar 201204, Uttar Pradesh, India.
2
Professor, Department of Paedodontics and Preventive Dentistry, D J College of Dental Sciences and Research, Modinagar 201204, Uttar Pradesh, India.
3
Reader, Department of Paedodontics and Preventive Dentistry, D J College of Dental Sciences and Research, Modinagar 201204, Uttar Pradesh, India.
4
Post Graduate Student, Department of Paedodontics and Preventive Dentistry, D J College of Dental Sciences and Research, Modinagar 201204, Uttar Pradesh, India.

Abstract

Stem cells are undifferentiated cells that can differentiate into specialized cells. Recently, enormous growth has been seen in the recognition of stem cell-based therapies, which have the potential to ameliorate the life of patients with conditions that span from Parkinson's disease to cardiac ischemia to bone or tooth loss. This research has produced new but unexplored possibilities in the regeneration of different organs and tissues. Presently, research is focused on the proficiency of stem cells and their utilization in dentistry, which is gaining interest. The tooth is nature's "esteem" for these precious stem cells and there are a number of these cells in permanent and primary teeth, as well as in the wisdom teeth. Dental stem cells are easy, convenient, and affordable to collect. They hold promise for a range of very potential therapeutic applications, such as in the treatment of cancer, spinal cord injury, brain damage, myocardial infarction, hearing loss, diabetes, wound healing, baldness, etc. Since these cells were used to regenerate damaged tissue in medical therapy successfully, it is possible that the dentist in future might use stem cell to regenerate lost or damaged dental and periodontal structures. This paper reviews the current concepts, characteristics of stem cells in regeneration, and its subsequent uses in dentistry.

KEYWORDS:

Dental stem cells; Regeneration endodontics; Stem cells; Tooth regeneration

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