Abstract
An oral prophylactic antibiotic regimen aiming at suppression of the gram-negative rods and yeasts of the bowel flora was utilised in 48 severely burned patients to prevent burn wound colonisation. Only 17% of the patients had an actual or potential infection. Only one Pseudomonas infection occurred. The effect of this selective gastro-intestinal decontamination is discussed.
MeSH terms
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Adult
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Amphotericin B / administration & dosage
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Anti-Infective Agents / therapeutic use*
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Burns / complications*
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Digestive System / microbiology*
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Drug Combinations / administration & dosage
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Drug Therapy, Combination
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Humans
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Polymyxins / administration & dosage
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Sulfamethoxazole / administration & dosage
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Tobramycin / administration & dosage
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Trimethoprim / administration & dosage
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Trimethoprim, Sulfamethoxazole Drug Combination
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Wound Infection / prevention & control*
Substances
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Anti-Infective Agents
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Drug Combinations
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Polymyxins
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Amphotericin B
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Trimethoprim, Sulfamethoxazole Drug Combination
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Trimethoprim
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Sulfamethoxazole
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Tobramycin