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J Photochem Photobiol B. 2017 Apr;169:96-100. doi: 10.1016/j.jphotobiol.2017.02.017. Epub 2017 Feb 24.

Biosynthesis of polyphenol-stabilised nanoparticles and assessment of anti-diabetic activity.

Author information

1
Department of Endocrine, Shanghai Huadong Hospital, Fudan University, Shanghai 200040, People's Republic of China.
2
Department of Pancreatic Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People's Republic of China.
3
Department of Pancreatic Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People's Republic of China; Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, People's Republic of China. Electronic address: shichen145@hotmail.com.

Abstract

Green synthesis of nanoparticles (NPs) is a major developing field. In this study, we utilised Whitania somnifera leaves as a green source to synthesise platinum (Pt) NPs. Synthesised Pt NPs resulted from controlled synthesis of 12nm spherical particles. The synthesised Pt NPs were subjected to anti-diabetic applications resulting in a significant decrease in plasma glucose levels after injecting the Pt NPs into streptozotocin-induced diabetic rats.

KEYWORDS:

Anti-diabetic activity; Controlled synthesis; Pt NPs; W. somnifera

[Indexed for MEDLINE]

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