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Gastroenterol Clin North Am. 1987 Dec;16(4):575-90.

Hepatocellular carcinoma: molecular biology, etiology and animal models.

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1
Liver Unit, University of the Witwatersrand Medical School, Johannesburg, South Africa.

Abstract

Hepatocellular carcinoma (HCC) occurs uncommonly in the United States and Western Europe, but is a relatively frequent neoplasm in sub-Saharan Africa, China, and the Far East. Environmental factors appear to determine the geographic clustering of the disease and to cause different spectrums of the disease in the high-incidence and low-incidence areas of the world.

PMID:
2831151
[Indexed for MEDLINE]
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