Format

Send to

Choose Destination
Roux Arch Dev Biol. 1986 Feb;195(2):123-127. doi: 10.1007/BF00456108.

Neural-inducing activity of nuclei and nuclear fractions from Xenopus laevis embryos.

Author information

1
Institut für Molekularbiologie und Biochemie, Freie Universiät Berlin, Arnimallee 22, D-1000, Berlin 33.

Abstract

From embryos (Xenopus laevis) of different developmental stages nuclei were isolated which exert neural inducing activity in the biological test. The active material could partly be extracted from the nuclei. Experiments for the isolation of nuclear ribonucleoprotein (RNP) particles have shown that the activity is localized at least in part in these particles. On the other hand, some neural inducer is not detached from chromatin and the nuclear matrix even with ionic detergents. Inducing activity was found in germinal vesicles and to a higher degree in the cytoplasm of oocytes, but in a masked, biologically inactive state.

KEYWORDS:

Embryonic induction; Nuclear fractions; RNP particles; Xenopus laevis

PMID:
28305447
DOI:
10.1007/BF00456108

Supplemental Content

Loading ...
Support Center