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Neurogastroenterol Motil. 2017 Sep;29(9). doi: 10.1111/nmo.13053. Epub 2017 Mar 17.

What's new in Rome IV?

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Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.
Drossman Gastroenterology, PLLC, UNC Center for Functional GI and Motility Disorders, Chapel Hill, USA.


The functional gastrointestinal disorders (FGIDs) are the most common disorders seen in Gastroenterology clinical practice. The Rome process has generated consensus definitions of FGIDS, allowing to subdivide patients into diagnostic categories based on the symptom pattern. The Rome IV consensus, presented in 2016, is the most recent update of this diagnostic scheme. This article summarizes the main changes, which include the use of epidemiology-based symptom thresholds to define FGIDs, characterization of FGIDS as disorders of Gut-Brain interaction, and updates of criteria for esophageal disorders, irritable bowel syndrome and Biliary and Sphincter of Oddi disorders based on scientific and technical progress made over the last decade. The Rome IV consensus provides a standard for clinical and research approach to FGIDS for the coming years.


functional bowel disorders; functional dyspepsia; functional gastrointestinal disorders; gallbladder and sphincter of Oddi disorders; symptom-based criteria

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