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J Clin Periodontol. 2017 May;44(5):520-529. doi: 10.1111/jcpe.12723. Epub 2017 Apr 27.

Long-term results of periodontal regenerative therapy: A retrospective practice-based cohort study.

Author information

1
Private Practice for Periodontology, Aachen, Germany.
2
Private Practice, Hattingen, Germany.
3
Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany.

Abstract

AIM:

Evaluation of the long-term effectiveness of regenerative treatment of intra-bony defects in periodontal practice.

MATERIAL AND METHODS:

A total of 1,008 intra-bony defects in 176 patients were analysed after using collagen-added deproteinized bovine bone mineral (DBBMc) with or without collagen membrane (CM) or enamel matrix derivative (EMD). Defects were classified as one- and two-wall and as shallow (≤6 mm), moderate (>6 and <11 mm) and deep (≥11 mm). Radiographic bone level changes were evaluated after 1 year, 2 to 4 years and 5 to 10 years.

RESULTS:

Mean radiographic defect fill was 3.8 mm after 1 year and remained stable up to 10 years. Deep and moderate defects showed a higher degree of fill than shallow defects (53.3%, 49.2%, 42.9%). Tooth loss amounted to 2.6%, was dependent on initial defect size (1.2% shallow, 1.4% moderate, 5.7% deep defects) and occurred mainly due to endodontic reasons.

CONCLUSIONS:

Within the limits of the retrospective study design, the findings indicate that periodontal treatment using DBBMc with or without CM or EMD can lead to long-term defect reduction and tooth survival for up to 10 years in the setting of a periodontal practice.

KEYWORDS:

bovine bone mineral; collagen; compliance; enamel matrix protein; long-term; membrane; radiographic bone level; regenerative periodontal therapy

PMID:
28303584
DOI:
10.1111/jcpe.12723
[Indexed for MEDLINE]

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