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Nat Rev Drug Discov. 2017 Apr;16(4):296. doi: 10.1038/nrd.2017.42. Epub 2017 Mar 17.

To cleave or not to cleave: therapeutic gene editing with and without programmable nucleases.

Author information

1
ETAGEN Pharma, Inc., Cambridge, Massachusetts 01239, USA.
2
Mouse Engineering Core Facility, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.
3
Massachusetts General Hospital, Cambridge, Massachusetts 02139, USA.
4
Gene Editing Institute for Translational Cancer Research, Helen F. Graham Cancer Center, and Research Institute, Newark, Delaware 19713, USA.
PMID:
28303022
DOI:
10.1038/nrd.2017.42
[Indexed for MEDLINE]

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