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Cardiol Young. 2017 Sep;27(7):1441-1443. doi: 10.1017/S104795111700035X. Epub 2017 Mar 16.

Prenatal diagnosis of aortopulmonary window associated with aberrant subclavian artery.

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1Division of Maternal-Fetal Medicine,Department of Obstetrics and Gynecology,University of South Florida Morsani College of Medicine,2 Tampa General Circle,Tampa,FL 33606,United States of America.
2Division of Pediatric Cardiology,Department of Cardiology,All Children's Heart Institute,601 5th Street,Saint Petersburg,FL 33701,United States of America.


Aortopulmonary window is a rare cardiac developmental anomaly characterised by a communication between the ascending aorta and the pulmonary artery. Aortopulmonary window may be isolated or associated with cardiac defects such as ventricular septal defect, atrial septal defect, interrupted aortic arch, and tetralogy of Fallot. We report a case of aortopulmonary window associated with aberrant subclavian artery based on fetal two-dimensional echocardiogram. The mother was referred for fetal echocardiography because of multiple fetal anomalies. Prenatal echocardiography at 30 weeks of gestation revealed a defect between the main and right pulmonary arteries and the ascending aorta (type III). The patient was born at 38 weeks of gestation via caesarean delivery, and was admitted to the neonatal intensive care unit because of respiratory failure and multiple congenital anomalies. Postnatal echocardiogram and cardiac MRI confirmed the prenatal findings. In addition, this patient had severe Dandy-Walker malformation and renal anomalies with poor prognosis. The family decided to withdraw respiratory care support on day of life 4, and the neonate passed away shortly after.


Aortopulmonary window; CHD; aortopulmonary septal defects

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