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J Rheumatol. 2017 May;44(5):594-598. doi: 10.3899/jrheum.160942. Epub 2017 Mar 15.

Deaths Associated with Ankylosing Spondylitis in France from 1969 to 2009.

Author information

1
From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France. praticlement@gmail.com.
2
C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté. praticlement@gmail.com.
3
From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France.
4
C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté.

Abstract

OBJECTIVE:

To describe deaths for which ankylosing spondylitis (AS) was on death certificates in France.

METHODS:

Death certificates in which AS was indicated were evaluated. Standard mortality ratio (SMR) was assessed.

RESULTS:

AS appeared in 2940 death certificates. The mortality rate of AS seemed stable. The most frequent initial causes were diseases of the circulatory system [28.3% in the International Classification of Diseases, 10th ed (ICD-10)]. SMR adjusted for age and sex were 2.1 (95% CI 1.45-2.91) for infections and 0.43 (0.36-0.5) for cancers (ICD-10 period).

CONCLUSION:

This study found an increase in mortality from infectious and external causes of death; conversely, patients with AS appear to die less frequently from cancer.

KEYWORDS:

ANKYLOSING SPONDYLITIS; DEATH CERTIFICATE; MORTALITY

PMID:
28298562
DOI:
10.3899/jrheum.160942
[Indexed for MEDLINE]

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