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Topical Atropine in the Control of Myopia.

Author information

1
Centro Oftalmologico Virgilio Galvis, Floridablanca, Colombia; Faculty of Health Sciences, Universidad Autonoma de Bucaramanga (UNAB), Floridablanca, Colombia.
2
Instituto Universitario Fernandez-Vega Oviedo, Spain.
3
Faculty of Health Sciences, Universidad Autonoma de Bucaramanga (UNAB), Floridablanca, Colombia.
4
Centro Oftalmologico Virgilio Galvis, Floridablanca, Colombia.
5
Faculty of Health Sciences, Universidad Autonoma de Bucaramanga (UNAB), Floridablanca, Colombia; Fundacion Oftalmol├│gica de Santander FOSCAL, Floridablanca, Colombia.

Abstract

Atropine has been used for more than a century to arrest myopia progression. Compelling evidence of its protective effect has been reported in well-designed clinical studies, mainly performed during the last two decades. However, its exact mechanism of action has not been determined. Experimental findings have shown that the mechanism is not related to accommodation, as was thought for decades. A review of the published literature revealed a significant amount of evidence supporting its safety and efficacy at a concentration of 1.0%, and at lower concentrations (as low as 0.01%).

KEYWORDS:

Myopia; Progression; Topical Atropine

PMID:
28293653
PMCID:
PMC5347209

Conflict of interest statement

Authors declared that the sponsors had not any role in the collection, analysis, and interpretation of data, in the writing of the manuscript, or in the decision to submit the manuscript for publication. Therefore, this funding source had not any kind of influence (or bias) in the work. All the aforementioned authors met the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have provided approval for the revised manuscript to be published.

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